The Sixth Edition has been thoughtfully restructured to provide clarity on difficult topics while maintaining the book’s general length and size. Both Chapters 2 and 3 on innate immunity have been reorganized for student-friendliness.
Please note that Chapter 12 has been split into two shorter, more focused chapters, becoming Chapter 12: Natural Killer Cells and Chapter 13: Unconventional Lymphoid Cells.
Chapter 1: Elements of the Immune System and Their Roles in Defense
Chapter 2: Innate Immunity: The Immediate Response to Infection
Chapter 3: Innate Immunity: The Induced Response to Infection
Chapter 4: Antibody Structure and the Generation of B-Cell Diversity
Chapter 5: Antigen Recognition by T Lymphocytes
Chapter 6: The Development of B Lymphocytes
Chapter 7: The Development of T Lymphocytes
Chapter 8: T Cell–Mediated Immunity
Chapter 9: Immunity Mediated by B Cells and Antibodies
Chapter 10: Preventing Infection at Mucosal Surfaces
Chapter 11: Immunological Memory and Vaccination
Chapter 12: Natural Killer Cells
Chapter 13: Unconventional Lymphoid Cells
Chapter 14: Failures of the Body’s Defenses
Chapter 15: Allergy and the Immune Response to Parasites
Chapter 16: Transplantation of Tissues and Organs
Chapter 17: Disruption of Healthy Tissue by the Adaptive Immune Response
Chapter 18: Cancer, Immunity, and Immunotherapy